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Symbol
Name
ID
Crb2
crumbs family member 2
MGI:2679260
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
Hydrocephalus
Ventriculomegaly
Gray matter heterotopia
Seizure
Disease(s) Associated with CRB2
ventriculomegaly - cystic kidney disease

Mouse Phenotypes
abnormal embryonic neuroepithelium morphology
open neural tube
hydrocephaly
dilated brain ventricle
abnormal Muller cell morphology
decreased retina photoreceptor cell number
abnormal retina bipolar cell morphology
short retina cone cell outer segment
short retina rod cell outer segment
abnormal retina cone cell outer segment morphology
abnormal retina cone cell morphology
Availability Mouse Genotype
Crb2tm1Vlcg/Crb2tm1Vlcg
Crb2tm1.1Wij/Crb2tm1.1Wij
Tg(Chx10-EGFP/cre,-ALPP)2Clc/0  (conditional)
Crb2tm1.1Wij/Crb2tm1.1Wij
Tg(Crx-cre)1Tfur/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory